Sclerosing peritonitis post liver transplantation: a rare condition where surgery is an important treatment option

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Excerpt

Sclerosing peritonitis (SP) is a rare but potentially fatal complication following orthotopic liver transplantation (OLT). This results in the peritoneum becoming thickened and inflamed, encasing the bowel in fibrous material forming cocoons that can then lead to malnourishment and bowel obstruction. The formation of the fibro‐collagenous ‘membrane’ can also contribute to refractory ascites and has been linked to liver allograft complications including biliary, inferior vena cava and porta hepatis obstruction.1 In the liver transplant population, the mechanisms leading to SP have been attributed to continuous peritoneal irritation from ascites and recurrent bacterial peritonitis.2 The natural history of SP post OLT is not well understood due to the rarity of the condition with the reported cases predominantly occurring weeks to months following transplantation.1 The aim of this study was to report on our experience with managing de novo SP in liver transplant recipients.
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