Unassisted return of spontaneous circulation after ventricular fibrillation
Cardiac monitoring at 2 a.m. showed AF and ventricular ectopics with identical coupling intervals. A few seconds later, an R‐on‐T wave phenomenon occurred causing an unstable rhythm followed by monomorphic and polymorphic ventricular tachycardia then ventricular fibrillation. Eventually, the rhythm degenerated into asystole for 9 seconds. Surprisingly, there was return of spontaneous electrical cardiac activity after this period (Fig. 1). He was initially presumed dead as two separate, independent assessments by a senior doctor and nurse during the episode found him unresponsive with absent pulses and respiratory effort. However, he “woke up” 2 minutes later and was hemodynamically stable. Unfortunately, he subsequently died 20 hours after the event.
Lazarus phenomenon was first described by Linko et al. in 1982. It is defined as delayed unassisted return of spontaneous circulation (ROSC) after cessation of cardiopulmonary resuscitation. This was a unique case where ROSC occurred in the absence of cardiopulmonary resuscitation attempts. The proposed mechanisms for Lazarus phenomenon are hyperinflation relating to rapid manual ventilation, myocardial stunning due to ischemia, or delayed action of medications due to poor venous return. None of these were applicable in our patient.