Treatment of Comorbid Bipolar Disorder Improves Disabilities and Neuropsychological Functioning in DiGeorge Syndrome: A Case Report

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To the Editors
Common manifestations of DiGeorge syndrome, also called 22q11.2 deletion syndrome (22q11.2 DS), include heart abnormalities at birth, subtle facial features, and learning disabilities1 with poor adaptive and neuropsychological functioning.2 Furthermore, mental disorders such as attention- deficit/hyperactivity disorder, anxiety disorders, and schizophrenia have frequently been associated with 22q11.2 DS.3 In addition, few cases of bipolar disorder (BD) have been reported.4 Lastly, an early cognitive decline has been described in patients with severe psychiatric comorbidities, including BD.
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