The presence of lymph node metastases (LNM) is considered one of the most important features of colorectal cancer (CRC) staging, indicating the need for additional surgery after local excision and adjuvant chemotherapy after surgery. Now, a new study challenges the role of LNM in the progression of CRC.
Refers to Naxerova, K. et al. Origins of lymphatic and distant metastases in human colorectal cancer. Science 357, 55-60 (2017)