Diffusion Tensor Imaging of Lumbar Vertebras in Female Adolescent Idiopathic Scoliosis: Initial Findings

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Abstract

Objective

The purpose of this study was to characterize diffusion tensor imaging (DTI) features of lumbar vertebras in adolescent idiopathic scoliosis (AIS) patients.

Methods

Fifty-two AIS patients and 20 healthy volunteers underwent 3-T magnetic resonance scanning including DTI sequence. The fractional anisotropy (FA) and apparent diffusion coefficient (ADC) values on the convex and concave sides of lumbar vertebras were obtained and compared.

Results

The FA and ADC values differed significantly between the convex and concave side of lumbar vertebras in AIS (P < 0.01). The ADC values in AIS differed significantly with healthy volunteers (P < 0.01). The FA values on the convex side of L1 to L2 were significantly lower than L4 to L5 in AIS. The difference of FA values between the concave and convex sides of the apex vertebra correlated significantly with Cobb angle (r = 0.436, P < 0.01).

Conclusions

The convex and concave sides of lumbar vertebras in AIS patients showed different DTI features.

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