Near-infrared autofluorescence imaging to detect parathyroid glands in thyroid surgery

    loading  Checking for direct PDF access through Ovid

Abstract

OBJECTIVE

To identify and save parathyroid glands during thyroidectomy by displaying their autofluorescence.

METHODS

Autofluorescence imaging was carried out during thyroidectomy with and without central lymph node dissection. After visual recognition by the surgeon, the parathyroid glands and the surrounding tissue were exposed to near-infrared light with a wavelength of 690-770 nm using a modified Karl Storz near infrared/indocyanine green endoscopic system. Parathyroid tissue was expected to show near infrared autofluorescence at 820 nm, captured in the blue channel of the camera.

RESULTS

We investigated 41 parathyroid glands from 20 patients; 37 glands were identified correctly based on near-infrared autofluorescence. Neither lymph nodes nor thyroid revealed substantial autofluorescence and nor did adipose tissue.

CONCLUSIONS

Parathyroid tissue is characterised by showing autofluorescence in the near-infrared spectrum. This effect can be used to identify and preserve parathyroid glands during thyroidectomy.

Related Topics

    loading  Loading Related Articles