powsimR: power analysis for bulk and single cell RNA-seq experiments

    loading  Checking for direct PDF access through Ovid

Abstract

Summary

Power analysis is essential to optimize the design of RNA-seq experiments and to assess and compare the power to detect differentially expressed genes in RNA-seq data. PowsimR is a flexible tool to simulate and evaluate differential expression from bulk and especially single-cell RNA-seq data making it suitable for a priori and posterior power analyses.

Availability and implementation

The R package and associated tutorial are freely available at https://github.com/bvieth/powsimR.

Contact

vieth@bio.lmu.de or hellmann@bio.lmu.de

Supplementary information

Supplementary data are available at Bioinformatics online.

Related Topics

    loading  Loading Related Articles