DynaPho: a web platform for inferring the dynamics of time-series phosphoproteomics
Large-scale phosphoproteomics studies have improved our understanding of dynamic cellular signaling, but the downstream analysis of phosphoproteomics data is still a bottleneck. We develop DynaPho, a useful web-based tool providing comprehensive and in-depth analyses of time-course phosphoproteomics data, making analysis intuitive and accessible to non-bioinformatics experts. The tool currently implements five analytic modules, which reveal the transition of biological pathways, kinase activity, dynamics of interaction networks and the predicted kinase-substrate associations. These features can assist users in translating their larger-scale time-course phosphoproteomics data into valuable biological discoveries.Availability and implementation
DynaPho is freely available at http://dynapho.jhlab.tw/.Contact
email@example.com or firstname.lastname@example.org.Supplementary information
Supplementary data are available at Bioinformatics online.