The nasoseptal flap has been widely used to reconstruct skull base defects with excellent success rates. Recently, there were several attempts to use this flap for other defects. Patient concerns: We present the case of the nasoseptal flap reconstruction after oropharyngeal cancer resection.Diagnosis:
The diagnosis of this patient was oropharyngeal T3 squamous cell carcinoma.Interventions:
The surgical resection included the right radical tonsillectomy, uvular, and part of the soft palate and hard palate. The nasoseptal flap was sutured to the oropharyngeal defect.Outcomes:
In spite of the radiation therapy, the nasoseptal flap was well healed to the oropharyngeal defect.Lessons:
We suggest that the nasoseptal flap may be a feasible reconstruction option for oropharyngeal defect after oropharyngeal cancer resection.