Managing panhypopituitarism in adults
LR, 56, WAS ADMITTED to a rural acute care hospital with a diagnosis of pneumonia. As a child of 6, he'd undergone surgery and radiation therapy to treat a malignant anterior pituitary gland tumor. This resulted in a deficiency of all anterior pituitary gland hormones. Called panhypopituitarism, this disorder includes deficiencies in growth hormone, thyroid-stimulating hormone, and adrenocorticotropic hormone.
Both authors cared for LR during this admission. Using his case as an example, the authors will discuss the pathophysiology of panhypopituitarism, significant diagnostic studies, and treatment related to this disorder. Identifying details have been changed to maintain patient confidentiality.