Corneal Endothelial and Myotonic Dystrophy

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To the Editor:
We read with great interest the article by Hering et al1 concerning a possible correlation between corneal endothelial dystrophy (CED) and myotonic dystrophy.
We conducted several studies in patients with myotonic dystrophy in the attempt to understand the reason for low intraocular pressure in these patients.2–5 In one of these studies, we examined the endothelial cell characteristics in these patients3 and found the endothelial cell characteristics to be normal, and no patients presented with CED.
We are wondering about possible explanations of such a difference. One could be that CED is a middle-age disease, and, maybe our patients were too young,6 but this is not the case, as the 2 cases reported by Hering et al were 26 and 44 years old, in the range the patients we studied.
Perhaps the severity or a subset of the disease not present in our patients, or a casualty could be the reason for the reported CED.

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