Alveolar soft part sarcoma with multiple brain and lung metastases in pregnancy: A case report and literature review

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Alveolar soft part sarcomas (ASPSs) with multiple brain metastases in pregnancy is a rare entity.

Patient concerns:

We report our experience with a 19-year-old pregnant woman who presented with intermittent headaches and vomiting at 38 weeks gestation.


The patient was initially diagnosed as brain metastasis according to computed tomography and magnetic resonance imaging (MRI) imaging.


Cesarean section and craniotomy (complete resection of both brain metastatic lesions) was performed sequentially.


A healthy baby girl was delivered safely and no neonatal malformations were found. Histological analysis confirmed the diagnosis of ASPS. Follow-up MRI performed 10 months after surgery revealed no residual tumor or signs of recurrence.


We report a case of ASPS with multiple brain and lung metastases in a pregnant woman. We recommend timely MRI examination for diagnosis and have discussed the approach to the treatment of pregnant women with brain metastasis.

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