Alveolar soft part sarcoma with multiple brain and lung metastases in pregnancy: A case report and literature review

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Abstract

Rational:

Alveolar soft part sarcomas (ASPSs) with multiple brain metastases in pregnancy is a rare entity.

Patient concerns:

We report our experience with a 19-year-old pregnant woman who presented with intermittent headaches and vomiting at 38 weeks gestation.

Diagnoses:

The patient was initially diagnosed as brain metastasis according to computed tomography and magnetic resonance imaging (MRI) imaging.

Interventions:

Cesarean section and craniotomy (complete resection of both brain metastatic lesions) was performed sequentially.

Outcomes:

A healthy baby girl was delivered safely and no neonatal malformations were found. Histological analysis confirmed the diagnosis of ASPS. Follow-up MRI performed 10 months after surgery revealed no residual tumor or signs of recurrence.

Lessons:

We report a case of ASPS with multiple brain and lung metastases in a pregnant woman. We recommend timely MRI examination for diagnosis and have discussed the approach to the treatment of pregnant women with brain metastasis.

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