New tool to tackle Alzheimer's disease: amyloid-β protofibril-selective antibody AbSL: An Editorial Highlight for ‘The conformational epitope for a new Aβ42 protofibril-selective antibody partially overlaps with the peptide N-terminal region’ on doi:10.1111/jnc.14211

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Abstract

This Editorial highlights a study by Colvin et al. (2017) in the current issue of Journal of Neurochemistry, in which the authors describe the development and characterisation of a new rabbit antibody (termed antibody St. Louis; AbSL) that preferentially recognises amyloid-β (Aβ) protein 42 (Aβ42) protofibrils over other Aβ species.

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