OESOPHAGUS: A new candidate for the progenitor cell of Barrett metaplasia

    loading  Checking for direct PDF access through Ovid

Abstract

At the squamocolumnar junction of mice and humans, a new study has identified a unique population of transitional basal cells that express molecular markers of both oesophageal stratified squamous epithelium and gastrointestinal columnar epithelium. These transitional basal cells are an attractive candidate for the cell of origin for Barrett oesophagus.

Refers to Jiang, M. et al. Transitional basal cells at the squamous-columnar junction generate Barrett's oesophagus. Nature550, 529-533 (2017)

    loading  Loading Related Articles