Comparing Health Related Quality of Life Outcomes in Patients Undergoing Either Primary or Revision Anterior Cervical Discectomy and Fusion

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Abstract

Study Design.

A retrospective review of prospectively collected data.

Objective.

Compare HRQOL outcome metrics in patients undergoing primary and revision ACDF.

Summary of Background Data.

Anterior cervical discectomy and fusion (ACDF) is associated with significant improvements in health related quality of life (HRQOL) outcome metrics. However, 2.9% of patients per year will develop symptomatic adjacent segment disease and there is a paucity of literature on HRQOL outcomes following revision ACDF.

Methods.

Patients were identified who underwent either a primary or revision ACDF, and who had both preoperative and a minimum of one-year post-operative HRQOL outcome data. Pre- and postoperative Short Form 12 Physical Component Score (SF12 PCS), Short Form 12 Mental Component Score (SF12 MCS) VAS neck, VAS arm and Neck Disability Index (NDI) scores were compared.

Results.

360 patients (299 primary, 61 revision) were identified. Significant improvement in SF12 PCS, NDI, VAS neck and VAS arm was seen in both groups, however only a significant improvement in SF12 MCS was seen in the primary group. When comparing the results of a primary versus a revision surgery, the SF12 PCS score was the only outcome with a significantly different net improvement in the primary group (7.23 +/- 9.72) compared to the revision group (2.9 +/- 11.07; p = 0.006) despite similar baseline SF12 PCS scores. The improvement in each of the other reported HRQOL outcomes did not significantly vary between surgical groups.

Conclusion.

A revision ACDF for cervical radiculopathy or myelopathy leads to a significant improvement in the HRQOL outcome, and with the exception of the SF12 PCS, these results are similar to those of patients undergoing a primary ACDF.

Conclusion.

Level of Evidence: 2

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