Insights into ablation of persistent atrial fibrillation: Lessons from 6‐year clinical outcomes

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Ablation of atrial fibrillation (AF) is an established treatment option for symptomatic, drug‐refractory patients.1 Pulmonary vein isolation (PVI) is currently the cornerstone of all ablation strategies for AF. Apart from PVI, ablation strategies for persistent AF are heterogeneous and mainly characterized by additional ablation of complex fractionated atrial electrograms (CFAE) and/or linear lesions.2 This study evaluates the long‐term clinical outcomes applying an ablation strategy that focuses on the critical role of circumferential PVI (CPVI) for symptomatic, drug‐refractory persistent AF, and identifies predictors for clinical efficacy.
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