Inhaled Anesthetics in Acute Lung Injury

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Excerpt

Lung injury is commonly seen in the intensive care units (ICUs), and its high morbidity and mortality has led to the exploration of multiple interventions for prevention and treatment. The most severe form of lung injury, the acute respiratory distress syndrome (ARDS), occurs in over 10% of all ICU admissions and accounts for the care of nearly a quarter of all ventilated patients worldwide.1 The broad clinical impact and heterogeneous clinical presentation of lung injury makes it a complex and challenging entity to manage. Despite rigorous research efforts to identify and mitigate factors causing significant lung injury, ARDS continues to confer an extreme level of unacceptable morbidity and mortality, thus intensifying the search for better therapeutics.

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