Periosteal Ewing Sarcoma in a 65-Year-Old Man: A Case Report

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Abstract

Case:

Ewing sarcoma is predominantly a pediatric bone malignancy involving the medullary canal. Periosteal Ewing sarcoma, a subtype arising from the periosteum, is exceedingly rare, with approximately 30 reported cases in the literature. We describe a case of periosteal Ewing sarcoma in the tibia of a 65-year-old man. Magnetic resonance imaging revealed a heterogeneous mass in the proximal tibial diaphysis without medullary involvement. The diagnosis was confirmed histologically after biopsy. The patient was treated with neoadjuvant chemotherapy, radical resection, and adjuvant chemotherapy.

Conclusion:

To the best of our knowledge, this case report describes the oldest documented patient with periosteal Ewing sarcoma.

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