Cross‐sectional associations of albuminuria among Aboriginal and Torres Strait Islander adults: the eGFR Study

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Excerpt

Albuminuria is an indicator of microvascular injury1, the metabolic syndrome, diabetic and non‐diabetic chronic kidney disease (CKD) and excess cardiovascular disease mortality.2 Guidelines have recently recommended CKD screening and staging using both albuminuria and estimated glomerular filtration rate (eGFR).2 Local and national clinical management guidelines for CKD also recommend renoprotective medication use.5
Albuminuria without impaired GFR,7 or which precedes diabetes is a common CKD presentation in Aboriginal and Torres Strait Islander (TSI) people of northern Australia. In this population, albuminuria has been linked with overweight, dialysis dependent end stage kidney disease (ESKD) and mortality.8 Understanding the associations of albuminuria among Aboriginal and Torres Strait Islander people, such as the consistency of clinical prescribing practices for adults with CKD, may highlight health system and broader health promotion measures for ESKD prevention. Our aim was to describe the clinical, anthropometric and biochemical associations of albuminuria among volunteering Aboriginal and Torres Strait Islander adults within different levels of kidney function living across large regions of northern and Central Australia.
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