Aripiprazole Treatment in a 9-Year-Old Child With OCD and Hypomania Symptoms Possibly Related to Herbal Medicines: A Case Report

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To the Editors
Herbal medicine constitutes the main source of treatment for most (75%–80%) of the world's population, especially in developing countries.1 Nevertheless, most herbal products currently do not have a requirement for a drug approval process to indicate their safety and effectiveness. Additionally, they may have several dangerous side effects, including psychiatric symptoms.2,3
Aripiprazole is a new atypical antipsychotic drug that acts as a partial agonist for dopamine (D2) and serotonin 1A receptors (5-HT1A) and an antagonist of serotonin 2A receptors (5-HT2A). It is used for various psychiatric disorders including schizophrenia, bipolar disorder, and aggressive behaviors.4–6 Several studies have reported that it may also have a beneficial effect on obsessive-compulsive disorder (OCD) as an adjunctive to selective serotonin reuptake inhibitor treatment.7
In this report, we present a case whose OCD and hypomania symptoms, which were possibly related to herbal medicine use, disappeared with aripiprazole treatment.
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