Giant Porokeratosis With Malignant Transformation to Squamous Cell Carcinoma

    loading  Checking for direct PDF access through Ovid

Excerpt

Porokeratosis is a disorder of epidermal keratinization. Clinically these lesions are notable for a raised rim of scale, and histologically they feature the pathognomonic finding of a coronoid lamella. Many variants of porokeratosis exist, and some have demonstrated an increased risk of malignant transformation.1 Immunosuppression has been identified as 1 predisposing factor for the development of porokeratosis.2 Patients with the history of renal transplantation also have an elevated incidence of porokeratosis.
    loading  Loading Related Articles