Atherosclerosis: cell biology and lipoproteins – focus on anti-inflammatory therapies

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Cardiovascular disease (CVD) continues to pose the worldwide leading cause of death in the general population. Atherosclerosis, the underlying disease of a majority of strokes and myocardial infarctions, is a lipid-driven, chronic disorder of the arterial vessel wall. Clinical and basic research over the past decades yielded evidence for involvement of the immune system in all stages of atherosclerosis ranging from lesion initiation and propagation to the final phase precipitating acute clinical symptoms [1,2].

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