Age of Infection with Kaposi Sarcoma Associated Herpesvirus and Subsequent Antibody Values Among Children in Uganda
We investigated associations between KSHV seroconversion age and KSHV antibody values in Ugandan children. Every annual delay in KSHV seroconversion age was associated with a reduction of 19% (p<0.0001) in K8.1 and 27% (p<0.0001) in ORF73 antibody values at age 6. Early infection may be an important risk factor for KSHV pathogenesis and viral shedding in saliva, leading to transmission.
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