Current Opinion in Urology. 9(4):297-302, JUL 1999

PMID: 10459464

Issn Print: 0963-0643

Publication Date: 1999/07/01


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Interstitial cystitis

Grannum Sant;Theoharis Theoharides;

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Abstract

Interstitial cystitis is a complex inflammatory condition of the bladder. The pathophysiology of interstitial cystitis is incompletely understood, although altered epithelial permeability, mast cell activation and sensory afferent nerve upregulation play critical roles. A unified understanding of the pathogenesis of interstitial cystitis is emerging and this will hopefully lead to the introduction of novel therapies for pain and irritative voiding symptoms. Interstitial cystitis is a common disease among women and is frequently misdiagnosed as prostatitis and benign prostatic hyperplasia among men.

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