A 62-year-old woman with a history of dry eyes was found to have unilateral pedunculated, nonpigmented palpebral conjunctival lesions. Excisional biopsy was performed, and the lesions were studied histopathologically. Microscopic examination of the lesions demonstrated exuberant granulation tissue with a granulomatous foreign body giant cell reaction surrounding pigmented and partially birefringent foreign material. Histopathologic examination of the patient’s cosmetics revealed that the pigmented foreign bodies seen on the biopsy specimens were compatible with her mascara and/or eyeliner. While cosmetics have been reported to have ophthalmic sequelae, palpebral lesions such as these have not been reported to the authors’ knowledge.