Radiosurgery for Intracranial Arteriovenous Malformations in Children1

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Background:The objective of this retrospective study is to determine the value of radiosurgery in the management of arteriovenous malformations (AVM) in the pediatric age group.Methods:From January 1994 through January 1999, thirty-one children with arteriovenous malformations (AVMs) were treated with radiosurgery. All patients were treated on an outpatient basis at the same institution by the same team. The Leksell Gamma Knife unit was used. Workup included angiography, MRI, and MRA. Follow-up ranged from 7 months to 67 months, with a median of 33 months. Minimum doses of radiation, depending on the size of the lesion, ranged from 20 Gy to 25 Gy. Treatment volumes for all the vascular malformations ranged from 0.6 cc to 17 cc with a mean volume of 4.7 cc. The mean number of isocenters was 4.8.Results:Total obliteration of AVM nidus was obtained in 22 of 31 (71%) patients, while 9 patients had partial obliteration. Stabilization of the benign lesions was obtained in all the patients treated. None had rebleeding after the procedure and, as of this writing, no patient required retreatment.Conclusion:Radiosurgery is an effective noninvasive and safe therapeutic modality for the management of vascular malformations independent of location, size, or grade.

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