CV events persist for one year after stopping Vioxx
US labelling for Raptiva updated, Boxed Warning added
The US FDA is consolidating drug safety information about prescription drugs for both patients and healthcare professionals at a single access point on its website.
Health Canada has advised consumers against using Powertabs and Sweet Energizer Vitality Candy,
Acute use of antipsychotics in the preceding 2 weeks is associated with significantly worse swallowing function,
Pooled analysis shows superior GI tolerability of celecoxib
Renal dysfunction: a possible late effect of high-dose methotrexate
LIFT substudy assesses endometrial effects of tibolone
Alcohol/dosulepin overdose : Intoxication, with symptoms including seizures and arrhythmias: 2 case reports
Aciclovir : Acute renal failure in children: 2 case reports
Adalimumab : Psoriasis: case report
Amisulpride/ziprasidone : Hyperprolactinaemia treated with aripiprazole: case report
Amoxicillin/clavulanic acid : Psychotic disorders: case report
Allopurinol : Acute generalised exanthematous pustulosis: case report
Amoxicillin/clavulanic acid : Cholestasis in an elderly patient: case report
Antineoplastics : Stomatitis treated with lafutidine: 3 case reports
Antiretrovirals/peginterferon-α-2a/peginterferon-α-2b/ribavirin : Oral lichenoid lesions: 2 case reports
Amoxicillin/linezolid : Klebsiella oxytoca haemorrhagic colitis (first report with linezolid): 2 case reports
Aripiprazole : Acute dystonia in a child: case report
Azathioprine : Elevated liver enzymes in an elderly patient: case report
Betamethasone/hydrocortisone : Leucocytosis (first report with hydrocortisone): case report
Azathioprine/mercaptopurine : Myelosuppression, treated with granulocyte colony stimulating factors: 2 case reports
Cetirizine : Dystonia in a child: case report
Bupivacaine/fentanyl : Subdural haematoma after spinal anaesthesia: case report
Bupivacaine : Respiratory failure following high spinal anaesthesia in an infant: case report
Bosentan : Autoimmune hepatitis in an elderly patient: case report
Carbamazepine : Cognitive changes: case report
Ciclosporin/mycophenolate mofetil/prednisone : Cholangiocarcinoma?: case report
Ciclosporin/prednisolone : Norwegian scabies?: case report
Ciprofloxacin : Fatal thrombocytopenia and haemolytic anaemia: case report
Ciclosporin : Hair darkening and hypertrichosis: case report
Clozapine : Fatal gastrointestinal disorders: case report
Deferiprone : Arthritis: case report
Dapsone : Photosensitivity: case report
Dipyrone : Haemolytic anaemia and various toxicities: case report
Didanosine/stavudine : Nonalcoholic steatohepatitis and cirrhosis: 2 case reports
Dextrose : Fatal hyponatraemia in a child: case report
Dicloxacillin : Mixed cholestatic liver injury in an elderly patient: case report
Doxifluridine : Chronic myeloid leukaemia (first report) in an elderly patient: case report
Donepezil : Pisa syndrome in elderly patients: 2 case reports
Disopyramide : Exacerbation of myasthenia gravis associated with respiratory insufficiency, cardiomyopathy and conduction disorders: case report
Fexofenadine : First report of eosinophilic hepatitis: case report
Erythromycin : First report of tongue and nail discolouration: case report
Estradiol congeners/sumatriptan : Ischaemic colitis: case report
Fludarabine-containing chemotherapy : Acute myeloid leukaemia: 2 case reports
Glatiramer acetate : Anaplastic large-cell lymphoma: case report
Heparin : Heparin-induced thrombocytopenia: case report
Herbal medicines : Liver injury: case report
Imipenem/meropenem : Neutropenia: case report
Hydroxycarbamide : Recurrent leg ulcers in an elderly patient: case report
Herbal medicines : Deep vein thrombosis and pulmonary embolism in elderly patients: 2 case reports
Interferon-β : Optic neuritis in an elderly patient: case report
Indometacin/methotrexate : Macrophage activation syndrome (first report with indometacin) associated with liver failure?: case report
Influenza virus vaccine : Giant cell arteritis in an elderly patient: case report
Infliximab : Tuberculous colitis: case report
Interferon-β-1a : Systemic scleroderma: case report
Lansoprazole : Collagenous colitis: case report
Methotrexate : Acantholytic dermatosis in an elderly patient: case report
Melatonin : First report of ulcerative colitis aggravation: case report
Morinda : Liver injury: case report
Multiple drug overdose : Liver injury, pneumonia (first report with benzethonium chloride and dibucaine), and renal failure (first report with benzethonium chloride, dibucaine and naphazoline): case report
Mifepristone/misoprostol : Uterine rupture: case report
Mexiletine : Drug hypersensitivity in an elderly patient: case report
Nitrofurantoin : Bronchiolitis obliterans organising pneumonia in an elderly patient: case report
Peginterferon-α-2b/ribavirin : First report of semen alterations and sperm DNA fragmentation: case report
Olanzapine : Weight gain: case report
Peginterferon-α-2b/ribavirin/tacrolimus : Transplant-related thrombotic microangiopathy: case report
Pegvisomant : Lipodystrophy, pituitary tumour enlargement and erythematous injection site reaction: 7 case reports
Peginterferon-α-2b/ribavirin : Vestibulocochlear toxicity: case report
Pneumococcal vaccine : Fever and cellulitis in children: 17 case reports
Propylthiouracil : Liver failure: case report
Polio vaccine live oral : Vaccine-associated paralytic poliomyelitis in an infant with a Bruton's tyrosine kinase mutation: case report
Purified talc : Talcoma: case report
Raltegravir-containing HAART regimen : Development of integrase inhibitor resistance in HIV-2 infection: case report
Sodium tetradecyl sulfate : Chronic facial pain: case report
Risedronic acid : Osteonecrosis of the jaw in an elderly patient: case report
Sulbactam/ampicillin : Cholestasis in an elderly patient: case report
Sirolimus : Hepatotoxicity: case report
Sunitinib : Hypothyroidism, hypertension and exudative pericarditis: case report
Sunitinib : Acute haemolysis: case report
Sulfasalazine : Myonecrosis due to Clostridium septicum infection: case report
Sumatriptan : Ischaemic colitis: case report
Terlipressin : Ischaemic skin necrosis in an elderly patient: case report
Tamoxifen : Endometriosis, uterine leiomyoma, sactosalpinx (first report), cystadenoma, and haemorrhage of the corpus luteum?: case report
Vancomycin : Thrombocytopenia: case report
Valproic acid : Liver failure: 4 case reports
Tetanus vaccine : First report of squamous cell cancer: case report
Zinc : Hypocupraemia leading to anaemia and neutropenia in an elderly patient: case report