Safety, QOL findings from phase III trial favour pazopanib
Dabigatran trial halted: warfarin more effective, excess bleeding
Topical corticosteroid use likely to be safe during pregnancy
US study compares rates of fluoroquinolone-related ED visits
Capillary leak syndrome with filgrastim, pegfilgrastim
Class-wide labelling changes tighten use of long-acting opioids
Zelboraf label to warn of cancer progression, DRESS syndrome
Risk differences between NSAIDs unclear, concludes MARC
Merck Serono Australia is recalling its 5.1 model Easypod auto injector, as the company is replacing it with a newer, safer model.
PRAC calls to restrict obstetric SABA use
The EMA has begun a review into the use of oral bromocriptine for preventing or suppressing lactation following childbirth.
Pfizer Canada has added information to the Product Monograph for the anticancer drug Sutent [sunitinb],
All rituximab users to be screened for hep B virus, risk of reactivation
Albendazole : Granulomatous hepatitis: case report
Alendronic acid : Lateral cortical thickening of proximal femur: case report
Agalsidase-α : Infusion-associated hypersensitivity reaction: 2 case reports
Abacavir/tenofovir : Rhabdomyolysis and acute kidney injury: case report
Adalimumab/etanercept : Merkel cell carcinoma in an elderly patient: case report
Amiodarone : Interstitial pneumonia: case report
Amitriptyline abuse : Central nervous system depression: case report
Amfetamine mixed salts/antiepileptic drugs/fluoxetine : Various toxicities: 2 case reports
Allopurinol : DRESS: case report
Amphotericin B liposomal : Anaphylaxis: case report
Amoxicillin/clavulanic acid : Kounis syndrome: case report
Amphotericin B : Injection site swelling and skin eruptions, and fever: case report
Antineoplastics : Mild fatigue and vomiting: case report
Anastrozole/carboplatin : Bilateral papilloedema (first report with anastrozole): case report
Asparaginase/mercaptopurine : Pancreatitis in paediatric patients: 2 case reports
Aripiprazole : Extrapyramidal symptoms: case report
Antineoplastics : Neutropenia, diarrhoea and neuropathy: 5 case reports
Antiretrovirals interaction : Fanconi's syndrome and osteomalacia: case report
Atomoxetine : Raynaud's phenomenon in a child: case report
Azathioprine : Pulmonary infarction leading to haemorrhagic necrosis and pneumothorax due to zygomycosis, and aspergillosis: case report
Atropine/fentanyl/rocuronium bromide : Respiratory distress syndrome in a neonate: case report
Baclofen/botulinum toxin A : Cephalalgia, sleepiness and resistance in spasticity: case report
BCG : SAPHO syndrome (first report) in an elderly patient: case report
Benzylpenicillin : Acute Jarisch-Herxheimer reaction: case report
Bevacizumab : Gastrointestinal perforation: case report
BCG : Disseminated infection following intravesical administration: 3 case reports
Bismuth : Subacute progressive encephalopathy: case report
Boceprevir/peginterferon/ribavirin : Fatal tuberculous sepsis (first report with boceprevir): case report
Brentuximab vedotin : Thrombocytopenia and polyneuropathy: case report
Buserelin/chorionic gonadotropin/triptorelin : Ovarian hyperstimulation syndrome: 6 case reports
Cabazitaxel : First report of liver toxicity: case report
Bupivacaine : Nystagmus and diplopia due to CSF leakage: case report
Caffeine/ergotamine abuse : Multivalvular heart disease: case report
Carbamazepine/lamotrigine/oxcarbazepine : DRESS syndrome, Stevens-Johnson syndrome and toxic epidermal necrolysis in paediatric patients: 4 case reports
Calcium carbonate overdose : Milk alkali syndrome: case report
Ceftriaxone : Pseudolithiasis: case report
Celecoxib : Bullous pemphigoid in an elderly patient: case report
Cetuximab/erlotinib/gefitinib/panitumumab : Various toxicities: 5 case reports
Cetuximab : Skin rash with secondary MRSA infection: case report
Ciclosporin/fluindione/rifampicin interaction : Bleeding in an elderly patient: case report
Ciprofloxacin : Skin eruption?: case report
Cisplatin : Acute multiple arterial thrombosis: case report
Cisplatin : Cholestatic hepatitis: case report
Ciclosproin/methylprednisolone/mycophenolate mofetil : Hairy cell leukaemia: case report
Cisplatin/docetaxel/fluorouracil : Acute pericarditis: case report
Clenbuterol abuse : Acute myocardial ischaemia: 2 case reports
Cisplatin/etoposide : Nausea, vomiting, and generalised myalgia: case report
Citalopram/rifampicin interaction : Recurrence of panic attacks: case report
Clobazam/dipotassium clorazepate : Prolonged coma: 2 case reports
Clozapine/citalopram/antiemetics : Serotonin syndrome: case report
Clozapine : Neutropenia: 6 case reports
Cotrimoxazole : Baboon syndrome/SDRIFE: case report
Cotrimoxazole/irbesartan/hydrochlorothiazide : Hyperkalaemia: case report
Dabigatran etexilate : Intracranial haemorrhage in elderly patients: 3 case reports
Cytarabine : Hand-foot syndrome: case report
Cytarabine/idarubicin : Febrile neutropenia, bacteraemia, and endophthalmitis: case report
Deferasirox/ifosfamide : Fanconi syndrome and renal failure: case report
Dabigatran etexilate : Renal atheroembolic disease in an elderly patient: case report
Dacarbazine : Thrombocytopenia: case report
Denosumab : Symptomatic hypocalcaemia: case report
Dabigatran etexilate : Wunderlich's syndrome in an elderly patient: case report
Dronedarone : Toxic hepatitis in an elderly patient: case report
Docetaxel : Exacerbation of subacute cutaneous lupus erythematosus: case report
Dexamethasone/nimesulide : Acute cholestatic hepatitis, haemorrhagic gastritis and hiccups: 2 case reports
Dexmedetomidine/felodipine/levothyroxine sodium : Hypernatraemia and polyuria in an elderly patient: case report
Efavirenz : Gynaecomastia in a child: case report
Fentanyl : Bradycardia following transdermal administration: case report
Erlotinib/gefitinib : Hair and scalp changes: 13 case reports
Fluorouracil/folinic acid/oxaliplatin : Growth restriction following in utero exposure: case report
Gentamicin : Retinal toxicity following subconjunctival use: case report
Galantamine : Weight loss in an elderly patient: case report
Gefitinib : Skin toxicity in an elderly patient: case report
Glucosamine : Hepatotoxicity: 4 case reports
Heparin : Heparin-induced thrombocytopenia?: case report
Hydrocortisone/mifepristone/prednisolone interaction : Aggravation of respiratory failure: case report
Hormones/hypnosedatives/olanzapine : Weight gain and worsening of sleep and psychiatric disorders: case report
Icodextrin : Masked hypoglycaemia in an elderly patient: case report
Hydroxycarbamide/nilotinib : Tumour lysis syndrome: 2 case reports
Hydromorphone : Pruritus following intrathecal administration: case report
Hydroxychloroquine : Posterior reversible encephalopathy syndrome: case report
Hydroxychloroquine : Renal phospholipidosis: case report
Infliximab : Interstitial lung disease: case report
Indapamide/omeprazole interaction : Hypomagnesaemia-induced hypocalcaemia in an elderly patient: case report
Infliximab : Primary biliary cirrhosis: case report
Immune globulin : Dyshidrotic eczema: case report
Interferon-β-1a : Renal thrombotic microangiopathy: case report
Ipilimumab : Multifocal radiculoneuropathy: case report
Infliximab : Pyoderma gangrenosum in an elderly patient with ulcerative colitis?: case report
Interferon-β-1a/methylprednisolone : Severe hepatitis and liver failure: 2 case reports
Lamotrigine : Acute hypersensitivity myocarditis: case report
Ketoconazole/mitotane : Neutropenia: case report
Lamotrigine : Stevens-Johnson syndrome: case report
Leflunomide : Hyperthyroidism: case report
Lenalidomide/rituximab : Serum sickness, acute tumour flare reaction and neutropenia: case report
Levofloxacin : Delirium: case report
Levodopa/carbidopa : Ataxic polyneuropathy: 4 case reports
Levofloxacin : Myasthenic crisis: case report
Lithium : Chronic lithium toxicity, acquired cystic disease and renal cell carcinoma in an elderly patient: case report
Lidocaine/phenytoin : Increased defibrillator pacing threshold and other toxicities in an elderly patient: case report
Metformin/rosiglitazone overdose : Various toxicities: case report
Methotrexate : Cutaneous ulcerations on psoriatic plaques and oral mucosa erosions in an elderly patient: case report
Methotrexate : Interstitial pneumonitis: case report
Methylprednisolone : Osteonecrosis of the femoral head: 3 case reports
Mizoribine : Hyperuricaemia and acute renal failure: case report
Mycophenolate mofetil : Shingles, abdominal pain and arthralgia in children: 4 case reports
Mycophenolate mofetil : Colitis: 5 case reports
Moxifloxacin/warfarin interaction : Abdominal wall haematoma and haemoperitoneum in an elderly patient: case report
Morphine overdose : Cardiac arrest and anoxic brain injury: case report
Nitrofurantoin : Interstitial lung disease and hepatotoxicity: case report
Nelarabine : Irreversible myelopathy: case report
Nilotinib : First report of psoriasis: case report
Nadroparin calcium : Calcinosis cutis at the application site: case report
Nevirapine : DRESS syndrome: case report
Oxycodone/naloxone : Opioid withdrawal syndrome: case report
Paclitaxel : Acute central nervous system toxicity: case report
Paclitaxel : Sinus bradycardia: case report
Panobinostat/sorafenib : Loss of appetite and weight loss in an elderly patient: case report
Peginterferon-α-2a : Erythema annulare centrifugum: case report
Paliperidone overdose : Sedation: case report
Paracetamol/various other drugs overdose : Suspected paracetamol poisoning: case report
Phenytoin/sirolimus interaction : Decreased serum sirolimus concentration in an elderly patient: case report
Piribedil : Premature ventricular contractions in elderly patients: 2 case reports
Peginterferon-α-2a/telbivudine : Lactic acidosis and rhabdomyolysis: case report
Phenprocoumon : Medial calcific sclerosis: 4 case reports
Povidone iodine : Iododerma following topical administration: case report
Prednisolone : Steroid psychosis: case report
Prednisolone/rifampicin : Pneumonitis in an elderly patient: case report
Potassium bromide : Bromoderma in an infant: case report
Pneumococcal 13-valent CRM197 vaccine conjugate : Sweet's syndrome: case report
Prednisone : Chronic gastritis, hypertension and borderline diabetes: case report
Propofol/rifampicin interaction : Hypotension: case report
Pregabalin abuse : Dependence, myositis and withdrawal symptoms: 2 case reports
Propranolol : Potentiation of apnoea of prematurity in an infant: case report
Proxymetacaine abuse : Toxic keratopathy: 7 case reports
Quinidine : Adverse gastrointestinal effects: case report
Rifampicin : Acquired Fanconi syndrome: case report
Pyridostigmine : Fasciculations and muscle cramps: case report
Ruxolitinib : Bilateral toxoplasmosis retinitis in an elderly patient: case report
Sirolimus : Late coronary artery aneurysm following drug-eluting stent implantation: case report
Sorafenib : Hyperpyrexia and skin rash: case report
Topiramate : Acute bilateral angle-closure glaucoma: case report
Tapentadol : Dizziness and tiredness in an elderly patient: case report
Triamcinolone : Severe acneiform rash, insomnia and cushingoid features: 4 case reports
Sulpiride : Hyperprolactinaemia, oligozoospermia and asthenozoospermia: case report
Voriconazole : Periostitis: 2 case reports
Valproic acid : Hyperammonaemic encephalopathy: case report
Warfarin : Calciphylaxis: case report
Vemurafenib : Erythema nodosum-like panniculitis: 2 case reports
Zuclopenthixol : Poisoning, leading to consciousness disturbance and akinesia in a child: case report