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To report a case of retinal vasculitis associated with Epstein–Barr virus infection.Case report.A 26-year-old woman came with blurry vision. Funduscopy illustrated vasculitis with frosted branch-like appearance. The patient was treated with systemic acyclovir and topical steroid. Circulating polymerase chain reaction was positive for Epstein–Barr virus antibodies. Two months of treatment resolved the clinical manifestations.Epstein–Barr infection should be considered as the etiology of retinal vasculitis with similar clinical manifestations.