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Salmonella infections are one of the most common agents of food-borne diseases. Brandenburg serovar is more common in animals than in humans, and previous reports has been published on suppurative thyroiditis, peritonitis, abscess of the thigh, abscess of the endometriosic ovarian-cyst and haemorrhagic urethritis caused by Salmonella Brandenburg infection.Our aim was to demonstrate a separate case of Salmonella Enterica subsp. enterica serovar Brandenburg infection in a male presenting with symptoms of gastroenteritis with hidradentis suppurativa in a 6-month period in 2014.This article reports an unusual case of a male prison guard with good physical and psychosocial condition aged (38), who developed gastroenteritis, displaying vomitus and progressive diarrhoea of 5-day duration in June 2014, but after the antibiotic therapy, his symptoms had not ended. The local family doctor had not taken stool samples. Four months later, hidradenitis suppurativa and rosacea was detected by the prison doctor. The first examination of the stool culture and smear was positive for S. Enterica subsp. enterica serovar Brandenburg in December 2014. After several and different therapies (including dermatologists) with antibiotics, proton-pump inhibition and other agents, a final diagnosis has been revealed as the Salmonella infection. Following an oral 14-day course of ciprofloxacin treatment and B6 vitamin supplementation, the patient displayed a significant clinical improvement.According to our best knowledge, this is the first article to report the case of Salmonella Brandenburg-associated chronic gastroenteritis, rosacea and axillar hidradenitis suppurativa.