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The aim of the study was to assess the prevalence of the skin diseases, dermatological conditions, and sexually transmitted infections among male prisoners.The medical data of 1800 inmates were analysed and a local sero-biological survey was performed in 2014. Moreover, after informed consent, dried blood spots were collected to identify recent hepatitis C virus (HCV) and HIV infections in case of homosexuality and intravenous drug use.Prisoners (n = 1800) were included in this study and 200 inmates with high risk of sexually transmitted disorder (STD) participated in serological tests. The most common dermatological diseases and STDs were atopic dermatitis (n = 70), scabies (n = 42), allergic reactions after insect bites (bedbug, mosquito, fly, and wasp) (n = 39), fungal infections (n = 1), psoriasis vulgaris (n = 10), eczema herpeticum (n = 1), erysipelas (n = 2), vasculitis (n = 1), and HCV (n = 2), whereas there were not found any HIV or gonococcal infections. Six HCV infections and zero HIV infections were determined in the study period.The present study shows a relatively high prevalence of infectious or atopic dermatitis among these populations.