Lung Injury After One-Lung Ventilation: A Review of the Pathophysiologic Mechanisms Affecting the Ventilated and Collapsed Lung

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(Abstracted from Anesth Analg, 121:302–318, 2015)

One-lung ventilation (OLV) enables complex intrathoracic surgeries but has also become a recognized risk factor for acute lung injury (ALI). It is associated with increased postoperative pulmonary complications and histologic/biochemical lung injury in patients.

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