Association Between Initial Fluid Choice and Subsequent In-Hospital Mortality During the Resuscitation of Adults With Septic Shock

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(Abstracted from Anesthesiology, 123:1385–1393, 2015)

No randomized controlled trial has studied the impact of different intravenous (IV) fluid mixture administration on resuscitation during severe sepsis. Current guidelines recommend IV crystalloids, such as isotonic saline (30 mL/kg administered within the first 6 hours during severe sepsis), but alternatives such as colloids and albumin are also frequently used.

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