Pregabalin Has Analgesic, Ventilatory, and Cognitive Effects in Combination With Remifentanil

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(Abstracted from Anesthesiology, 124:141–149, 2016)

Pregabalin is commonly used preoperatively as an analgesic. However, the use of pregabalin in combination with opiates—although standard clinical protocol in some settings—has remained controversial, as past studies of this practice have shown conflicting results with regard to effectiveness and safety.

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