Anesthesia-Related Carbon Monoxide Exposure: Toxicity and Potential Therapy

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(Abstracted from Anesth Analg, 123(3):670–681, 2016)

This article aims to detail anesthesia-related carbon monoxide (CO) exposure, identify its sources, review the mechanisms of overt CO toxicity, highlight the cytoprotective effect of low-dose CO at the cellular level, and discuss the potential therapeutic role for CO in routine anesthetic management. Both exogenous and endogenous sources of CO exposure are detailed here with an overview of the biologic effects of the gas and policy regarding the exposure and its overt toxicity.

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