The Effect of Dexmedetomidine Pretreatment on the Median Effective Bolus Dose of Propofol for Facilitating Laryngeal Mask Airway Insertion

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Abstract

(Abstracted from J Anesth, 31:11–17, 2017)

This study aimed to investigate the effect of 1 μg/kg of dexmedetomidine pretreatment on the median effective dose (ED50) of propofol when used to facilitate successful laryngeal mask airway (LMA) insertion by comparing it with a control group who received only propofol. Smooth insertion of LMA is essential for patient safety, and swallowing or coughing during placement could prevent accurate seating of the LMA or cause dislodgement of a correctly positioned LMA.

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