Potent Opioid Analgesia Without Respiratory Depression: Could It Be Possible?

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(Abstracted from Anesthesiology, 125(5):841–843, 2016)The first use of opioids for analgesia dates back to 4000 BC, and opioids remains one of the most potent drugs for pain management even today. Despite their continued efficacy, the adverse effects remain a matter of grave concern and can be life threatening.

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