Vasopressin Versus Norepinephrine in Patients With Vasoplegic Shock After Cardiac Surgery: The VANCS Randomized Controlled Trial

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(Abstracted from Anesthesiology, 126(1):85–93, 2017)The purpose of this prospective, double-blind, randomized controlled trial was to gauge whether vasopressin is superior to norepinephrine in reducing postoperative complications in patients with vasoplegic syndrome. This complication, which presents in 5% to 25% of cardiac surgery patients, is characterized by low arterial pressure with either normal or elevated cardiac output but reduced systemic vascular resistance.

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