The Effect of Melatonin on Early Postoperative Cognitive Decline in Elderly Patients Undergoing Hip Arthroplasty: A Randomized Controlled Trial

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(Abstracted from J Clin Anesth, 39:77–81, 2017)

Postoperative cognitive decline (POCD) is a common complication following surgery, especially in elderly patients (aged >60 years). Overall sleep loss and sleep fragmentation have been known to negatively impact cognitive performance, thus emphasizing the need to improve postoperative sleep quality to ameliorate POCD.

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