OSTEOARTHRITIS – THE BROAD VIEW
RISK FACTORS FOR DEVELOPMENT AND PROGRESSION OF HIP OSTEOARTHRITIS (OA)
DOXYCYCLINE (DOXY) SLOWS THE RATE OF JOINT SPACE NARROWING (JSN) IN PATIENTS WITH KNEE OSTEOARTHRITIS (OA)
UPREGULATION OF IL-1 INDUCIBLE GENES IN JOINT TISSUES AND PBMCS OF PATIENTS WITH OSTEOARTHRITIS (OA)
CONTROL OF CHONDROCYTE DIFFERENTIATION
MOLECULAR REGULATION OF GENE EXPRESSION IN CHONDROCYTES BY INFLAMMATORY MEDIATORS
IL-1ß AND TNF-α STIMULATE A POTENTIAL REPAIR RESPONSE IN HUMAN OSTEOARTHRITIC CHONDROCYTES VIA INDUCTION OF BMP-2
THE LINKAGE OF CHONDROCYTE DEATH AND MATRIX DEGRADATION
THE PROCESS IN CARTILAGE LEADING TO DESTRUCTION INCLUDES BOTH ANABOLIC AND CATABOLIC EVENTS
THE COLLAGEN FABRIC OF JOINT CARTILAGES
‘SMALL LEUCINE-RICH PROTEOGLYCANS: MULTIPLE ROLES IN MUSCULOSKELETAL TISSUES’
MECHANISMS INVOLVED IN CARTILAGE DEGRADATION IN DEGENERATIVE JOINT DISEASE
CARTILAGE COLLAGEN TURNOVER IN OSTEOARTHRITIS
ADAMTS-4 AND ADAMTS-5 IN CARTILAGE MATRIX BREAKDOWN AND THEIR INHIBITION BY TIMP-3
ARE METALLOPROTEINASES THERAPEUTIC TARGETS IN HUMAN DISEASE
THE DEVELOPMENT OF PATHOLOGY, ITS DETECTION AND REGULATION
AGGRECAN KNOCK-IN MICE ARE RESISTANT TO PROTEOLYSIS BY MMP OR ADAMTS ENZYMES IN THE INTERGLOBULAR DOMAIN
MURINE MODELS OF OSTEOARTHRITIS
MECHANICAL REGULATION OF CHONDROCYTE GENE EXPRESSION AND BIOSYNTHESIS IN CARTILAGE EXPLANTS
BASIC FGF
DIFFERENTIAL RESPONSES TO MECHANICAL STIMULATION IN NORMAL AND OSTEOARTHRITIC CHONDROCYTES
REGENERATION OF ARTICULAR CARTILAGE
GENE ENHANCEMENT OF CHONDROGENIC MATRIX PRODUCTION
CHONDROCYTES FOR CARTILAGE REPAIR
DEVELOPMENTAL PARADIGMS TO CARTILAGE TISSUE ENGINEERING
GENETICS OF OSTEOARTHRITIS AND DISEASE PROGRESSION
MOLECULAR GENETIC INVESTIGATIONS OF OSTEOARTHRITIS
ASSOCIATION OF FUNCTIONAL MUTATIONS WITHIN THE SECRETED FRIZZLED-RELATED PROTEIN 3 (sFRP3) GENE WITH HIP OSTEOARTHRITIS IN FEMALES
THE CHONDRODYSPLASIAS
MOLECULAR PORTRAYING OF OSTEOATHRITIC CHONDROCYTES BY GENE EXPRESSION ANALYSIS
PROTEOMIC ANALYSIS OF ARTICULAR CARTILAGE – IDENTIFICATION OF ACTIVIN A AS AN ANABOLIC REGULATOR
ADENOVIRAL GENE TRANSFER INTO CELLS FROM DISEASED TISSUE AS A TOOL TO INVESTIGATE THE REGULATION OF INFLAMMATORY AND DESTRUCTIVE MEDIATORS IN THE OSTEOARTHRITIC SYNOVIUM
THE EFFECT OF CYTOSKELETAL DISRUPTION ON ARTICULAR CARTILAGE CHONDROCYTE METABOLISM
STROMELYSIN (MMP-3) PLAYS A PIVOTAL ROLE IN SPONTANEOUS OSTEOARTHRITIS
MAGNETIC RESONANCE (MR) IMAGING OF DISTAL TARSAL OSTEOCHONDRAL STRUCTURE
EXPLOITING MOLECULAR KNOWLEDGE OF OA PATHOPHYSIOLOGY TO DEVELOP A VALIDATION TOOLBOX
A TYPE IX COLLAGEN INTERACTION WITH FIBRONECTIN
MICROVASCULAR PERICYTES EXHIBIT CHONDROGENIC POTENTIAL IN VITRO
LINEAGE TRACING REVEALS ARTICULAR AND EPIPHYSEAL CHONDROCYTES HAVE DISTINCT ORIGINS
AGGRECAN DEGRADATION OF CATABOLICALLY-STIMULATED CARTILAGE EXPLANTS IS INHIBITED BY TIMP-3
INVESTIGATION OF THE PKR SIGNALLING PATHWAY IN THE SYNOVIAL JOINT
QUANTITATIVE AND QUALITATIVE ANALYSES OF DATA FROM A GENOME-WIDE SCAN FOR NODAL OSTEOARTHRITIS IDENTIFIES TRAIT DEPENDANT SUSCEPTIBILITY LOCI
ACTIVATION OF INFLAMMATORY SIGNALLING PATHWAYS, AND INDUCTION OF IL-1 IN ARTICULAR CARTILAGE UPON EXPLANTATION AND CUTTING
PROTEOMIC ANALYSIS OF ARTICULAR CARTILAGE; A DISEASE PHENOTYPE IN OSTEOARTHRITIS?
THE EFFECTS OF n-3 POLYUNSATURATED FATTY ACIDS ON COX-2 AND PGE2 PROTEIN LEVELS IN ARTICULAR CARTILAGE CHONDROCYTES
THE POTENTIAL ROLES OF EPIGENETIC CHANGES IN DNA METHYLATIONS IN THE ALTERED GENE EXPRESSION OF OSTEOARTHRITIC CHONDROCYTES
ADAMTS-4 ACTIVITY ON A PROTEOGLYCAN VERSUS A POLYPEPTIDE IS CONTROLLED BY THE ANCILLARY DOMAINS
EXPRESSION PROFILING OF METALLOPROTEINASES AND INHIBITORS IN CARTILAGE
MATRIX METALLOPROTEASE- AND AGGRECANASE-GENERATED AGGRECAN FRAGMENTS IN HUMAN ARTICULAR CARTILAGE AND SYNOVIAL FLUIDS FROM OA PATIENTS
ASSAY DEVELOPMENT FOR OSTEOARTHRITIS TARGET DISCOVERY
AGE RELATED CHANGES IN HUMAN MENISCAL GLYCOSAMINOGLYCANS
AN EXAMINATION OF THE SPATIAL AND TEMPORAL EXPRESSION OF MARKERS OF ENDOCHONDRAL OSSIFICATION IN THE ARTICULAR CARTILAGE OF THE DUNKIN HARLEY GUINEA PIG
FUNCTIONAL SCREENING FOR VALIDATED OA TARGETS USING ARRAYED ADENOVIRAL KNOCK-IN AND KNOCK-DOWN LIBRARIES
ISOFORMS OF ADAMTS-4 AND -5 IN THE ECM OF CHONDROCYTE-AGAROSE CULTURES
THE EFFECT OF A MATRIX METALLOPROTEINASE INHIBITOR ON THE PROTEOGLYCAN METABOLISM OF INTERMITTENTLY LOADED CARTILAGE EXPLANTS
PERLECAN IN LATE STAGES OF OSTEOARTHRITIS OF THE HUMAN KNEE JOINT
ANTI-INFLAMMATORY ACTIONS OF GREEN TEA CATECHINS AND LIGANDS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS (PPARS)
THE ROLE OF ACETYLATION IN TIMP-1 REGULATION
PROTEOLYTIC ACTIVITY OF ADAMTS-4 EXPRESSED BY C-TERMINAL PROCESSING
MODULATION OF BONE MORPHOGENETIC PROTEIN (BMP) EFFECTS ON CHONDROCYTES BY ALTERED LEVELS OF THE C-FOS PROTO-ONCOGENE
COMPARATIVE STUDY OF FOAM AND FIBRE POLYMER SCAFFOLDS FOR CARTILAGE TISSUE ENGINEERING
INTEGRIN DEPENDENT UP-REGULATION OF PROTEOGLYCAN SYNTHESIS IN CULTURED NORMAL HUMAN ARTICULAR CHONDROCYTES FOLLOWING MECHANICAL STIMULATION IS LOST IN CHONDROCYTES FROM PATIENTS WITH OSTEOARTHRITIS AND RHEUMATOID ARTHRITIS
MECHANOTRANSDUCTION PATHWAYS IN CHONDROCYTES ARE ALTERED IN OSTEOARTHRITIS
IMAGING HUMAN ARTICULAR CHONDROCYTES UNDER SHEAR
NMDA EXPRESSION AND ROLES IN HUMAN ARTICULAR CHONDROCYTE MECHANOTRANSDUCTION