We report the detection of an earthquake by a space-based measurement. The Gravity Recovery and Climate Experiment (GRACE) satellites observed a ±15-microgalileo gravity change induced by the great December 2004 Sumatra-Andaman earthquake. Coseismic deformation produces sudden changes in the gravity field by vertical displacement of Earth's layered density structure and by changing the densities of the crust and mantle. GRACE's sensitivity to the long spatial wavelength of gravity changes resulted in roughly equal contributions of vertical displacement and dilatation effects in the gravity measurements. The GRACE observations provide evidence of crustal dilatation resulting from an undersea earthquake.