Seminars in Respiratory and Critical Care Medicine. 28(4):441–450, AUG 2007
PMID: 17764061
Issn Print: 1069-3424
Publication Date: 2007/08/01
Pulmonary Manifestations of Systemic Lupus Erythematosus
Beatrice Memet;Ellen Ginzler;
+ Author Information
1Division of Rheumatology; 2Department of Medicine, State University of New York-Downstate Medical Center, Brooklyn, New York
Abstract
Systemic lupus erythematosus (SLE) can affect the lung in multiple ways. All components of the respiratory system, including the pleura, pulmonary parenchyma, airways, vessels, and respiratory muscles can be involved in various degrees at some time in the disease course and contribute to its morbidity and mortality. This article reviews the clinical symptoms, imaging techniques, histopathology, prognosis, and treatment of pulmonary manifestations of SLE and the related disorder mixed connective tissue disease (MCTD), from a historical perspective and with regard to new insights into pathogenesis and therapy.
