MR Imaging of Bone Metastases and Choice of Sequence: Spin Echo, In-Phase Gradient Echo, Diffusion, and Contrast Medium

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Magnetic resonance imaging (MRI) is the only imaging technique allowing the direct visualization of the bone marrow and is the most sensitive to detect bone metastases. Sensitivity is high, but a good understanding and an informed choice of acquisition sequences can easily improve specificity. Fat and water distribution (spin echo), indirect visualization of bone trabeculae (in-phase gradient echo), evaluation of bone edema and cell density (diffusion), and the study of vascularization (contrast medium) should be cleverly combined to enable good detection and lesion characterization.

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