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Ligament injuries are among the most common injuries in sports and recreational activity. In an analysis of national registry data in England, incidence rates of ligament injury in soccer, basketball, hockey, volleyball, judo, and karate accounted for 36% to 75% of injuries.1 Failure to restore the function of ligaments leads to significant joint instability and sometimes limits the sports activities of athletes and further the development of degenerative arthritis during patients' active and productive ages. Therefore, proper management of ligament injuries is important. This article focuses on the clinical problems of ligament healing in the knee joint.