Objective: The Alberta Stroke Program Early CT score (ASPECTS)method is a validated score for identifying patients more likely to benefit from either thrombolytic or endovascular therapy. The e-ASPECTS software is a new, commercially available, standardized and fully automated ASPECTS scoring tool. e-ASPECTS assesses signs of early ischemic change on plain CT scans of stroke patients by applying the ASPECTS method. We compared the performance of e-ASPECTS to CT perfusion in detecting early ischemic signs.
Methods: e-ASPECTS was run on the plain CT scans of 20 patients with acute ischemic stroke. CT perfusion, CT angiography and 24h CT was also available. The ischemic damage identified by e-ASPECTS was compared to the ischemic core as depicted on CBV on CT perfusion and the established infarct core on plain CT at 24h.
Findings: e-ASPECTS reliably depicted established ischemic damage as compared to CT-Perfusion, both on an region-based and ASPECTS-based analysis.
Conclusion: This is the first report demonstrating that e-ASPECTS correctly identified infarct on plain CT, similar to CT perfusion.