Abstract TP150: Incidence of Vascular Cognitive Impairment After the First-ever Stroke in Korea

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Objective: This study aimed to analyze the incidence of vascular cognitive impairment (VCI) and factors influencing on VCI after the first-ever stroke.

Materials and Methods: This is the interim result of the Korean Stroke Cohort for Functioning and Rehabilitation (KOSCO) designed as 10 years long-term follow-up investigating functions and quality of life. From August 2012 to May 2015, 4,490 patients completed Korean Mini-Mental Status Examination (K-MMSE) at 7 days, 3 months, 6months and 1year after stroke.

Results: Among 4,490 patients, 77.2% of patients were ischemic and 22.8% hemorrhagic stroke, respectively. Their mean age was 64.3 and the gender ratio was 1.32:1 (M:F). Out of total patients, 1,596 patients (49.6%) suffered from cognitive impairment at 7 days; mild (MMSE 21 to 24) 16.0%, moderate (MMSE 11 to 20) 16.6%, severe (MMSE 0 to 10) 17.0 %, respectively. At 1 year after onset, some of patients showed improvement, however, 1,035 patients (32.2%) still showed to have cognitive impairment; mild 12.6%, modereate10.7%, and severe 8.9%, respectively. Factors influencing to cognitive impairment after stroke were age, initial severity of stroke and the duration of education (p<0.05). There was significantly better improvement of cognitive function at 1 year in patients who received inpatient rehabilitation (p<0.05).

Conclusion: This study revealed the incidence and characteristics of cognitive recovery in patients with first-ever stroke in Korea. Results supported a recommendation to commence intensive rehabilitation during the hospitalization period to improve cognitive function.

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