Background and Purpose: Patients with stroke often stop medication for the prevention. Medication behavior is mainly composed the medication compliance and understanding of the medication. The purpose of this study was to assess change in the medication behavior during one year after initial stroke, and to identify the correlation between medication compliance and understanding of the medication in patients with mild ischemic stroke.
Methods: Thirty-one patients with initial mild ischemic stroke were prospectively recruited. Two types of self-reported questionnaires (Medication compliance questionnaires, Understanding of medication questionnaires) were applied at admission (baseline) and 1 year after stroke respectively. Understanding of medication questionnaires contained 4 factors; “motivation”, “capacity”, “understanding” and “drug cost” for the medication. Change in the medication was analyzed by Wilcoxon signed rank test. The correlation between the medication compliance and understanding of medication were analyzed by Spearman’s rank correlation. The p-values<0.05 were considered statistically significant.
Results: Among the patients who agreed to participate in this study, 71% were males and 29% were females, with the average age of 66.0±8.4. Lacunar was the most common type of stroke among those patients. Their scores of medication compliance at 1 year after stroke were significantly increased (p<0.01) compared to those in the baseline. Their scores of understanding of medication“the drug cost burden” were also significantly increased (p<0.05).At baseline, there was significant correlation between medication compliance and understanding of medication“hassle for taking medicine”(ρ=0.464,p<0.01 ),“simple medication ” (ρ=0.528,p<0.01 ).At 1 year after stroke, there was significant correlation between medication compliance and understanding of medication“hassle for taking medicine” (ρ=0.381,p<0.05).
Conclusions: These data suggest that the estimation of drug cost and hassle for medication primarily affects the medication compliance. Nurses need to focus on not only the medication compliance but also the motion and cognitive function.