Abstract WP419: Predictors of Post-Discharge Physical Activity in Patients With Mild Ischemic Stroke

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Introduction: Low daily physical activity (PA) is a risk for stroke recurrence. However, the predictors of PA have not been well investigated in mild ischemic stroke (MIS). This study aimed to identify the predictors of PA after discharge in MIS.

Methods: We performed a single center registry, prospective observational study. Acute MIS with modified Rankin Scale (mRS) of 0-2 were consecutively enrolled. Baseline examination during hospitalization consisted of age, gender, National Institute of Health Stroke Scale, mRS, Mini-Mental State Examination, stroke subtype, cerebral white matter lesions, body mass index, blood pressure, ankle brachial index, blood laboratory tests, metabolic syndrome, handgrip strength, knee extensor isometric muscle strength (KEIMS), 10m maximum walking time, decisional balance for exercise, self-efficacy for walking (SE-W), social support for exercise (SSE), anxiety and depression. PA was measured at 6-months post-discharge by electronic accelerometer. The mean daily step counts and time of moderate to vigorous-intensity (≥3 Metabolic Equivalents) PA (MVPA) were used as an index of PA (total counts over 7 days/7). For multiple logistic regression analysis, step counts and MVPA were categorized into two groups divided by each median value. The baseline variables which had P <0.10 in the univariate analyses of step counts or MVPA were entered into the multiple logistic regression analyses with adjustments of age and gender.

Results: 163 MIS (115 male, 69.5±10.1 years) were successfully followed for 6-months post-discharge. After multivariate analyses, KEIMS (increment of 0.1 Nm/kg: OR=0.829, 95%CI=0.717-0.959, p=0.011), SE-W (increment of 1 point: OR=0.917, 95%CI=0.850-0.989, p=0.025) and SSE (increment of 1 point: OR=0.882, 95%CI=0.789-0.987, p=0.029) for step counts, and SE-W (increment of 1 point: OR=0.930, 95%CI=0.867-0.999, p=0.047) for MVPA were selected as independent predictors.

Conclusions: The findings of the present study suggest that an appropriate target group of low-PA MIS can be identified by simple measurements/questionnaires during hospitalization.

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