Abstract TP357: Risk Factors of Stroke Among Community- residing Patients with Chronic Obstructive Pulmonary Disease (copd)

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Introduction: Worldwide, chronic obstructive pulmonary disease (COPD) and stroke are leading causes of death. Increasing evidence suggests that COPD patients have a higher risk of stroke than the general populationObjectives: This study was undertaken to investigate risk factors of stroke including concurrent cardiovascular disease(CVD); to explore differences of these variables and their relationships according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) stage among community-residing patients with COPD.Methods: A total of 118 participants with mean aged 69.4 years old were recruited among those patients with COPD who have been treated at the outpatient department of pulmonology at a University hospital in an urban area of South Korea. Along with BP and anthropometric measurement, trained interviewers interviewed participants with a structured questionnaire including demographic characteristics, lifestyle risk factors, and comorbid CVD. Data were analyzed using SPSS statistics 20.0Results: Most of participants (89.8%) were men, almost half (50.4%) of them were categorized into GOLD stage II, and 39.3 % and 10.3 % of them were GOLD stage III and IV, respectively. Mean systolic BP of participants was 123.8 mmHg and mean diastolic BP, 80.3 mmHg. Seventy percent of them were currently non-smoker and 45% of them did not drink. Sixty eight percent of them had no CVD, while 32% of them had been diagnosed with and treated due to hypertension, atrial fibrillation, or coronary artery diseases. The duration of COPD diagnosis was significantly shorter among those who had comorbid CVD. There were no significant differences in histories of smoking or drinking according to the GOLD stages. However, those in GOLD stage II had more CVD than those in COLD stage III and IV. Also, age and BMI showed significant differences according to the GOLD stages.Conclusions: The findings demonstrated the presences of stroke risk factors and possible associations between some risk factors, such as comorbid CVD, and COPD severity among patients with COPD. Further research is needed to explore the precise relationships among stroke risk, concurrent CVD, and the severity, duration, treatment of exacerbations of COPD among this population.

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