Abstract WP265: Debunking the Myth of Regular Soda Beverages Use and the Risk of Incident Cardiovascular Events

    loading  Checking for direct PDF access through Ovid

Abstract

Objective: The goal of this study was to determine the effect of soda beverage intake on occurrence of cardiovascular in diseases in a large prospective cohort of postmenopausal women.

Methods: The data were analyzed for 93, 676 women 50-79 years of age who were enrolled in the observational arm of the Women’s Health Initiative Study. The effect of regular soda beverage intake (none or minimal, non-caffeinated, and caffeinated) on risk of ischemic stroke, hemorrhagic stroke, any stroke, myocardial infarction, and cardiovascular deaths was determined over a period of 12 ± 1 years (mean ± SD) using Cox proportional hazards analysis after adjusting for age, ethnicity, body mass index, systolic blood pressure, diabetes, cardiac catheterization, atrial fibrillation, and high cholesterol.

Results: The rates of diabetes mellitus were higher among regular non-caffeinated and caffeinated soda beverage users compared with those with none or minimal use. Compared with women who were non-users or <1 /month, regular non-caffeinated soda beverage users (>1/wk) had a lower risk of myocardial infarction (hazards ratio [HR] 0.9, 95% confidence interval [CI] 0.8 - 1.0, p<0.02), and cardiovascular death (HR 0.8, 95% CI 0.7-1.0, p=0.02). Compared with women who were non-users or <1 /month, regular caffeinated soda beverage users (>1/wk) had a lower risk of any stroke (HR 0.89, 95% CI 0.80-1.0, p=0.05), hemorrhagic stroke (HR 0.69, 95% CI 0.0.47 - 0.97, p=0.034), and myocardial infarction (HR 0.90, 95% CI 0.81-1.0, p=0.056).

Conclusions: There appeared to be no increase in risk of incident cardiovascular events in women using non caffeinated or caffeinated soda beverages despite higher rates of underlying diabetes mellitus.

Related Topics

    loading  Loading Related Articles